Does collagen have a globular or fibrous tertiary protein structure?

Collagen is classified as a fibrous protein, which is reflected in its structure and function. Fibrous proteins, like collagen, are typically characterized by their elongated, rope-like conformations that provide structural support and tensile strength to various tissues in the body.

Collagen, in particular, comprises triple helical structures made up of polypeptide chains rich in glycine, proline, and hydroxyproline. This unique triple helix contributes to its stability and ability to form extensive networks, which is crucial for the integrity of connective tissues such as tendons, ligaments, cartilage, and skin. The fibrous nature of collagen is integral to its role in maintaining the architecture of these tissues, allowing them to withstand stretching and provide resistance against mechanical forces.

While other proteins, such as enzymes or antibodies, exhibit globular shapes that are more compact and functional in nature, collagen’s fibrous structure is designed specifically for mechanical support rather than enzymatic activity or transport—highlighting the distinction in functionality between fibrous and globular proteins.