Which polysaccharide is predominantly found in the cornea?

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Keratan sulfate is a specific type of glycosaminoglycan, which is a component of the extracellular matrix found in various tissues, including the cornea. It plays a crucial role in maintaining the structural integrity and transparency of the corneal tissue. In the cornea, keratan sulfate helps to provide resistance to compressive forces and contributes to the hydration of the tissue, which is essential for its clear and transparent properties.

Hyaluronic acid is also a component found in the body, particularly in connective tissues; however, it is more prominent in synovial fluid and serves a different function than keratan sulfate in the cornea. Glycogen and starch are storage forms of glucose found primarily in liver and muscle tissues (glycogen) and in certain plants (starch), but they do not have a significant role in the corneal structure. Thus, keratan sulfate is the predominant polysaccharide in the cornea due to its unique properties that support corneal function and health.

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