Which Vitamin is critical for turnover of epithelial tissue and goblet cell function?

Vitamin A is essential for the proper turnover of epithelial tissue and is critical for the function of goblet cells, which are responsible for secreting mucus in various mucosal surfaces, particularly in the respiratory and gastrointestinal tracts. This vitamin plays a vital role in maintaining healthy vision, skin, and epithelial cell integrity.

Retinoids, which are derived from vitamin A, are involved in the regulation of gene expression and cellular differentiation. This is particularly important in epithelial tissues, where vitamin A helps in the production and maintenance of the cells necessary for the integrity and protective functions of these tissues.

Deficiency in vitamin A can lead to problems such as impaired mucosal barriers, increased susceptibility to infections, and a range of epithelial issues, highlighting its crucial role in cellular turnover and function.